BUY WITH CONFIDENCE
Good for you, Good for your body
Protect Cognitive Function
Increase Energy Metabolism
Slow Aging
Reduce Oxidative Stress
Compounds
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Nicotinamide DUO™
400mg Mono + 100mg Riboside
Nicotinamide DUO™ from Perpetua.Life® Biotech is an 80/20 blend of Mono/Riboside, which has been found to boost NAD+ level even higher than Riboside alone. NAD+ is essential for energy metabolism, DNA repair, and gene expression [study1, study2]. NAD+ levels decline with age, linked to physical decline and age-related diseases like Alzheimer’s. Studies show supplementing with NAD+ precursors restores NAD+ levels and prevents age-related decline [study]
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Fisetin
100mg (from Japanese Wax Tree)
Fisetin, a flavonoid compound, acts as a senotherapeutic, eliminating senescent "zombie" cells. It targets growth signaling pathways and plays a significant role in Chronic Diseases [study]. Fisetin shows potential as an anticancer agent, offering cancer prevention and pharmacotherapy [study]. Studies in rodents suggest it reduces senescent cell numbers and extends lifespan [study]. Additionally, Fisetin serves as a dietary antioxidant for promoting health [study]
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Quercetin
250mg (from Sophora japonica)
Quercetin, a flavonoid found in plants and red wine, has antioxidant and anti-inflammatory effects. It may combat cancer cells, control blood sugar, and aid heart health. With potential chemo-preventive properties, it shows promise in cancer prevention and therapy [study]. Quercetin also influences circadian clock genes and aging-related genes [source].
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Trans-Resveratrol
150mg (from Japanese Knotweed)
Trans-Resveratrol, a polyphenol in grapes, berries, and red wine, activates sirtuin genes, promoting longevity. It improves oxidative stress, kidney health, and prevents periodontitis. Also, it regulates circadian clock and aging-related genes[source].
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Astragalus
150mg (from Astragalus membranaceus)
Astragalus, a traditional Chinese herb, combats aging by reducing oxidative stress and boosting immune function. It activates the PI3K/AKT/mTOR pathway, promoting cellular autophagy. Astragalus also shows promise in protecting against inflammation and gastrointestinal cancers. Moreover, it holds potential as a telomerase activator for anti-aging therapies [source].
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Epigallocatechin Gallate (EGCG)
100mg (from Camelliea sinesis)
EGCG, abundant in green tea, has diverse health benefits, including reducing cancer and heart disease risk. It promotes longevity by restoring mitochondria, activating AMPK, and inducing cellular autophagy. EGCG intake is linked to reduced all-cause mortality, diabetes, stroke, and heart disease-related death risk. Animal studies suggest protection against UV-induced skin aging [source 1, source 2, source 3].
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Trimethylglycine
85mg (as Betaine Anhyrous)
TMG effectively controls blood homocysteine levels, associated with heart disease and stroke. It may reduce cancer deaths, protect against lung cancer, and improve memory and brain function in seniors. TMG is also being studied as a potential treatment for neurological disorders like Alzheimer's [source].
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L-Theanine
100mg
L-theanine, an amino acid in teas and mushrooms, may protect against mental decline and extend roundworms' lifespan by around 5%. It shows promise in attenuating liver aging, reducing inflammation, and acting as a neuroprotective agent. L-theanine also prevents long-term side effects of adolescent THC exposure [source].
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Spermidine
10mg (as Spermidine Trihydrochloride)
Spermidine possesses anti-inflammatory and antioxidant properties, enhances respiration and metabolic function, and may reduce the risk of cancer, metabolic disease, heart disease, and neurodegeneration. Additionally, it improves memory and slows cognitive decline by clearing Alzheimer's-related amyloid-beta plaques through autophagy, making it potentially beneficial for older individuals with mild dementia [source].
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Piperine
10mg (from Piper Nigrum)
The primary value of piperine in health supplements is its ability to enhance the bioavailability of some other vitamins and minerals. This mechanism is still being studied, but piperine is known to inhibit the enzymes P-glycoprotein and CYP3A4 in humans. These enzymes are involved in the metabolism and transport of various metabolites. Animal studies also show that piperine inhibits CYP 450 enzymes that metabolize many drugs. In particular, piperine may increase the bioavailability of curcumin by a factor of 20.
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Vitamins B (B2, B6, B12)
B2 - 1mg || B6 - 5mg || B12 - 250mcg
As the building blocks of a healthy body, B vitamins have a direct impact on your energy levels, brain function, and cell metabolism. B vitamins may help prevent infections and help support or promote energy levels (B2), eyesight (B2), proper nerve function (B2, B6), cell health (B6), growth of red blood cells (B6, B12), brain function (B2), cardiovascular health (B6, B12), muscle growth & recovery (B6, B12)
